Tamoxifen gynecomastia

Discussion in 'Web Medical Information' started by impossible, 19-Aug-2019.

  1. AlexSher Well-Known Member

    Tamoxifen gynecomastia


    Gynecomastia is a common and sometimes distressing condition that may occur in males of all ages. Although most cases have benign causes and many are self-limited, male breast enlargement may also be a sign of underlying systemic disease or drug toxicity. Although rare, male breast cancer must also be considered in the differential diagnosis. A careful diagnostic evaluation should be pursued, tailored to the individual patient’s circumstances. Treatment may include reassurance, medication, or surgery. The Endocrine Society is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Endocrine Society has achieved Accreditation with Commendation. In order to use Medscape, your browser must be set to accept cookies delivered by the Medscape site. Medscape uses cookies to customize the site based on the information we collect at registration. The cookies contain no personally identifiable information and have no effect once you leave the Medscape site.

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    Treatment should be directed at correcting any underlying reversible causes. If gynecomastia is idiopathic, reassurance of the common, transient and benign nature of. When you're a young guy with puffy nipples it affects your social life and confidence negatively in any way you can imagine. In this article, I will teach you the. Alternatively, he could be offered testosterone supplementation or tamoxifen therapy, with a good chance that his gynecomastia would decrease in size and.

    BACKGROUND: Idiopathic gynecomastia is a benign breast disorder characterized by overdevelopment of male breast tissue. It can cause discomfort and concern, resulting in patients seeking diagnosis and treatment. We aimed to evaluate the efficacy of tamoxifen therapy in resolving this condition. METHODS: We undertook a prospective cohort study of all male patients who presented to our breast clinic, were diagnosed with primary gynecomastia, and were treated with a trial of tamoxifen 10 mg daily therapy, over a 10-year period from October 2004 to October 2015. All patients underwent routine investigations to exclude secondary causes of gynecomastia. Of these, 28.4% were bilateral gynecomastia and 71.6% were unilateral. The end point of interest was the complete resolution of gynecomastia. The majority (87.7%) of cases presented with accompanying mastalgia. Following treatment, 90.1% (n = 73) had a complete response of their gynecomastia with tamoxifen therapy. Pubertal gynaecomastia affects up to 70% of male adolescents, with the highest prevalence occurring at 14 years of age. While spontaneous regression occurs in 90% of cases within three years, until then, symptoms of mastodynia and psychological distress are prevalent in some patients prior to surgical treatment. Tamoxifen, a selective oestrogen receptor modulator (SERM), given at 20 mg daily for six months, was found to be a safe, well-tolerated and effective alternative treatment to current therapeutic options of watchful waiting (no management) and invasive cosmetic surgery. No adverse effects were observed in hormonal and auxological studies. The patient presented was able to avoid undergoing surgery, which should be reserved for persistent gynaecomastia present at the end of puberty after failing a trial of tamoxifen. Randomised controlled trials (RCTs) are needed for definitive therapeutic recommendations.

    Tamoxifen gynecomastia

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  6. AIMS We aimed to confirm suggestions that tamoxifen therapy alone may resolve. Drug Administration Schedule; Gynecomastia/drug therapy*; Gynecomastia/.

    • Management of physiological gynaecomastia with tamoxifen. - NCBI.
    • Approach to the Patient with Gynecomastia The Journal of Clinical..
    • Tamoxifen a promising therapeutic option for gynecomastia - On..

    Gynecomastia is defined as benign proliferation of glandular breast tissue. Tamoxifen and raloxifene Evista are effective for preventing and. Tamoxifen, a selective oestrogen receptor modulator SERM, given at 20 mg. effects of raloxifene and tamoxifen in the treatment of pubertal gynecomastia. In recent years, anti-estrogens have been increasingly used empirically for symptomatic gynecomastia. Tamoxifen given orally at doses of 20.

     
  7. soccerrooney Guest

    Hallo Ihr Lieben, bin neu hier, deshalb weiss ich nicht, ob dieses Thema schon fters behandelt wurde. Anfangs hatte ich hauptschlich Hitzewallungen, die aber mommentan etwas weniger sind. Aber wir beobachten einfach weiter meine uglein , er nimmt meine Sorge ernst, das ist schn. Aber es wre trotzdem nett, wenn sich jemand melden wrde. Seit einiger Zeit plagen mich Knochen- und Gelenkschmerzen. Sie haben sich bis jetzt brigens nicht grossartig verndert . Ich habe die ersten zwei Jahre Tamoxifen und Zoladex bekommen und hatte relativ schnell Schmerzen am ganzen Krper, so wie wenn man Fieber hat. Manchmal mehr, machmal weniger, manchmal gar nicht. Denn vor der Einnahme hatte ich knochenmig berhaupt keine Probleme. Nur eine linsentrbung, die aber vom cortison, die hab ich schon lnger.. Das nchste Mal sagst Du ihm dass es doch sehr positiv ist dass er ebenso altert. Und nach lngerem sitzen fhlte ich mich wie hundert. War schon beim Frauenarzt, Hausarzt und beim Orthopden. Aufgrund starker Rckenschmerzen (sind zum Glck wieder weg) musste ich schon zum Knochenszinti . Summa summarum: hab nur hitzewallungen, toi-toi-toi!! Ich hab Tamoxifen fnf Jahre genommen und hatte die selben Probleme mit den Knochen,jetzt ist alles wieder in Ordnung. Hitzewallungen waren auch ziemlich heftig, genau wie schlafstrungen. Erstmal tat sich gar nichts, inzwischen habe ich aber wieder einen Zyklus, seit kurzem erst, seither sind die meisten Zipperlein weg. Niemand kann mir sagen, ob es von den Tabletten kommt. Aber am meisten Probleme macht mir mein rechter Knchel. Kleine Hitzewellchen hab ich noch, aber absolut selten, Gelenke tun gar nicht mehr weh (also bis auf das bliche, Rckenschmerzen hab ich andauernd, aber das war vorher auch schon so und jnger bin ich inzwischen ja auch nicht geworden ). Es ist mal wieder ein Blockade am unteren Rckenbereich. Liebe Gre Ich nehme seit fast zwei Jahren Tamoxifen. Eine Bekannte von mir, die 5 Jahre Tamoxifen eingenommen hat, hat mir genau solche Schmerzen besttigt. Welche Nebenwirkungen können unter Tamoxifen auftreten. Tamoxifen und die Nebenwirkungen - BRIGITTE Community PharmaWiki - Tamoxifen
     
  8. Inferno3000 Moderator

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