Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data. Can i take plaquenil and adipex together Plaquenil use and weight Plaquenil maintenance dosage Aug 14, 2017 Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Hydroxychloroquine has an extremely long half life of around 32 days. This means that every 32 days, half of the previous amount of hydroxychloroquine in the body disappears. It takes around 5.5 half lives for a drug to be completely eliminated from your body meaning that you may need to wait for around 176 days. Please check with the appropriate physician regarding health questions and concerns. The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Hydroxychloroquine how long does it stay in body Long-Term Side Effects of Plaquenil for Rheumatoid., Taking Plaquenil for Rheumatoid Arthritis Tylenol plaquenil On average it would take over 8 months for all the hydroxychloroquine to be gone from a person’s body. Some women may choose to stop taking this medication before becoming pregnant; however, it’s important not to stop any medications before talking with a health care provider. Hydroxychloroquine MotherToBaby. How long does Hydroxychloroquine stay in your system?. Plaquenil Oral Uses, Side Effects, Interactions.. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but serious eye problem. Less than one person in 5,000 develops the problem.