If you have recently been diagnosed with polycystic ovary syndrome, you are not alone. The condition affects 5% to 15% of women of reproductive age. The condition occurs when the ovaries release elevated levels of androgens (male hormones). Ovulation doesn’t occur and follicles don’t break down, instead, they are filled with fluid which turns into cysts. The ovaries may swell in size and may become two to five times bigger than normal. Conception is a challenge due to overproduction of androgens. What causes PCOS is a mystery; however, many physicians associate it with hormonal imbalances, high levels of androgens as well as genetics. Metformin (or Glucophage) for polycystic ovararian symdrome (PCOS)by Kelly Why would you be taking metformin or glucophage (metformin is the generic for glucophage)Metformin is a diabetes medicine used for lowering insulin and blood sugar levels in women with polycystic ovary syndrome (PCOS). Then added a second pill at lunch time (so I took 1000 mg for 3 weeks). The second time that I took metformin, I increased the dosage from 500 mg to 1500 mg over the course of three weeks. This helps regulate menstrual cycles, start ovulation, and lower the risk of miscarriage in women with PCOS. I was sick a lot but I feel like I got the worst part over with faster. The first time I took it, I took 500 mg for about three weeks (1 pill in the morning). It is generally suggested that you start with the lowest dose and keep increasing it as you get used to it (or as the side effects start to go away). I’ve been to a number of different doctors who have all suggested different ways to work up to my maximum dosage (1500 mg). It does get better as time goes on but working myself up to the maximum dosage has always been hard. Problems that might arise and ways to troubleshoot I have always had pretty strong side effects (lots of nausea and always very tired) while taking metformin. 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If you have a diagnosis of PCOS it’s very likely that at some point your doctor has suggested Metformin. I personally was what would be considered the “perfect” candidate for this treatment when I was in my 20s and suffering with PCOS – overweight, struggling with acne and a complete lack of periods. However, I never tried it myself – instead I created a protocol for myself that became Metformin is a first-line medication for those suffering with type 2 diabetes. It is also presented as a treatment for PCOS sufferers who are also overweight or obese. Not all PCOS sufferers have weight gain as a symptom, it depends on the kind of PCOS. Women with the kind of PCOS that causes weight gain are usually insulin resistant. 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