Metoprolol is used alone or in combination with other medications to treat high blood pressure. It also is used to prevent angina (chest pain) and to improve survival after a heart attack. Metoprolol also is used in combination with other medications to treat heart failure. Metoprolol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. I used to take a slow-release Propranolol 80 mg every day, which caused severe tiredness and extreme fatigue, to the point that I was not able to think straight and sometimes could not even get out of bed. Apparently, Propranolol also inhibits the ability for you to burn fat, not to mention gastrointestinal issues. Depression is also significantly higher when taking Propranolol. So, I switched to Metoprolol and started off at its lowest dose: 25 mg extended release, which is obviously not enough, though I feel great in terms of strength and alertness and stamina, that were all seriously diminished when I was taking Propranolol. So, now I am wondering: I definitely need to go up at least to 50 mg, but should I do a 50 mg Metoprolol once a day, or can I take the 25 mg tablets twice a day (every 12 hours). My question is basically this: Would it be OK if you took a sustained-release medicine (that is supposed to stay in your blood for 24 hours) twice a day? Would there be a cumulative effect that could be dangerous perhaps? Prednisone west ward 473 Zoloft dose for depression Antabuse and vinegar Diflucan breastfeeding OTHER NAMES Metoprolol Su-Hydrochlorothiaz Tablet, Extended Release 24 Hr See also Warning section. Take this medication by mouth with or without food as directed by your doctor, usually once. I don't think any retard-release drug can actually maintain a good therapeutic level for 24 hours, so taking them every 12 hours seems to be alright, but I don't know the mechanism with which it releases gradually, thus wondering if taking Metoprolol 25 mg slow-release every 12 hours would be safe. Im already on 100 mg 1 time a day of extended release Metoprolol. I think, just to appease me, because ive had a couple really really bad days of almost n. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when you suddenly stop this drug. Some people who have suddenly stopped taking similar drugs have had chest pain, heart attack, and irregular heartbeat. If your doctor decides you should no longer use this drug, he or she may direct you to gradually decrease your dose over 1 to 2 weeks. When gradually stopping this medication, it is recommended that you temporarily limit physical activity to decrease strain on the heart. Get medical help right away if you develop chest pain/tightness/pressure, chest pain spreading to the jaw/neck/arm, unusual sweating, trouble breathing, or fast/irregular heartbeat. Show More This medication is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. I have been taking a beta blocker, 50 mg Metoprolol ER (Extended/Slow Release), for several years but have with my cardiologist approval today refilled my BB prescription with Metoprolol Tartrate (normal release) to be taken at 25 mg twice a day (every 12 hours). My reason is driven mainly by the fact the Tartrate is about 1/6th the cost of the Suc (ER). That said, I wonder if I will not in fact have a more "level" medication concentration taking the 25 mg twice rather than the 50 mg ER once a day. I think there is a good possibility that I'll have a more uniform medication concentration (on average) taking the Tartrate twice a day. Or, I have my doubts about how well a ER holds up over 24 hours. I doubt that I'll have anything to report, i.e., there will not be any change in my symptoms that I can detect. It seems I have the same opportunity to save money on my CCB by taking a normal release at half the dose twice a day. I'll discuss this with my cardiologist on my next 6 month regular check up, that assume I'll (hopefully) not have to seem him sooner. I must be the only one who "worries" about drug costs, and I have a private insurance plan connected to CVS. Metoprolol slow release Metoprolol Succinate Extended-Release Tablets, USP 25 mg, Slow-Release Meds for Arrhythmia and Anxiety - Suhagra 100 buy online Metoprolol oral tablet is available as generic drugs and as brand-name drugs. Brand names Lopressor and Toprol XL. Metoprolol comes as immediate-release. Metoprolol Side Effects, Dosage, Uses, and More - Healthline. Metoprolol extended release - MedHelp. Metoprolol - Wikipedia. Metoprolol comes as a tablet and an extended-release long-acting tablet to take by mouth. The regular tablet is usually taken once or twice a day with meals or immediately after meals. The extended-release tablet is usually taken once a day. To help you remember to take metoprolol, take it around the same times every day. Metoprolol comes as a tablet and an extended-release tablet to be taken orally. The regular tablet is usually taken once or twice a day with meals or immediately after meals. The extended-release tablet is usually taken once a day. To help you remember to take metoprolol, take it around the same time every day. Metoprolol succinate extended- release tablet administered once a day, and immediate release metoprolol administered once to four times a day, provided comparable total beta 1 -blockade over 24 hours area under the beta 1 -blockade versus time curve in the dose range 100–400 mg.