Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Can you drink alcohol when your taking plaquenil Hydroxychloroquine and sunlight eyes Can i take plaquenil and benadryl Hydroxychloroquine is used widely for the treatment of systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatologic conditions. It is now being considered for new applications in diabetes mellitus, heart disease, and adjunct cancer therapy. Fundus autofluorescence FAF is a non-invasive retinal imaging modality used in clinical practice to provide a density map of lipofuscin, the predominant ocular fluorophore, in the retinal pigment epithelium. Multiple commercially available imaging systems, including the fundus camera, the confocal scanning laser ophthalmoscope, and the ultra-widefield imaging device, are available to the. Hydroxychloroquine Retinopathy-Fundus Autofluorescence. Fundus autofluorescence image of a 46-year-old woman with systemic lupus erythematosus who had taken chloroquine for 17 years at a dosage of 500 mg/d. Based on her actual body weight, which was ideal, she had been overdosed at 8.8 mg/kg/d and had received a cumulative dose of 3102 g of hydroxychloroquine. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Fundus autofluorescence hydroxychloroquine Hydroxychloroquine toxicity - EyeWiki, Clinical applications of fundus autofluorescence in retinal. Fundus autofluorescence hydroxychloroquine Hydroxychloroquine. fundus autofluorescence imaging. This produces. an image of the retina that can detect abnormal levels of a substance called lipofuscin in the retina; this may be an early sign of disease. The results of the tests may be assessed after you. Eye screening for patients taking hydroxychloroquine.. Hydroxychloroquine Retinopathy-Fundus Autofluorescence - The.. Hydroxychloroquine and Chloroquine Retinopathy.. Ivocal signs of chloroquine maculopathy bilateral peri-central scotoma in the visual fields, structural alterations of the macula in the optical coherence tomography but normal or atypical findings as to fundus autofluorescence imaging. Results In all patients, optical coherence tomography showed perifoveal thinning and subtle alterations of the outer retinal layers. In one patient, the. Fundus autofluorescence FAF is an objective imaging test that uses the properties of the RPE to detect early toxicity. In early hydroxychloroquine toxicity, FAF often shows subtle parafoveal hyperautofluorescence, thought to be related to increased lipofuscin activity in the RPE. 4 In later stages of disease, hypoautofluorescence will be noted. To investigate the application of ultra-widefield fundus autofluorescence UWF-FAF imaging in evaluating hydroxychloroquine HCQ retinopathy and to report peripheral autofluorescence findings in Asian patients with this condition.