After the fevers I get severe chilblains on my fingers, ears and toes. This I have always attributed to the Raynauds I was diagnosed with as a child. Effects of plaquenil on skin Contraindications of methotrexate and plaquenil Chloroquine autophagy lysosome Chloroquine pharmacology Aug 26, 2016 I went to see a new rheum and he took me off the Plaquenil to see what symptoms would show. I have not been formally diagnosed yet. It took 6 weeks to see the results. I went into a bad flare. Went back to rheum and he decided to put me on Methotrexate. I have only taken it once, so I am not sure what the results will be. Yes, plaquenil has helped me a lot. I once went off it, against my rheumatologist's advice. That showed me how much it was helping, because I got progressively worse after stopping it. However, the Plaquenil did nothing for the RA, and it is very dangerous for your eyes, so I went off. I have never had a lung problem from mthx, either, although when I went of mthx and Kineret, my biologic for a recent foot reconstructive surgery, I got a vocal fold nodule, and now I can barely talk. Going off methx just exhausted me. So the reason for the post is to know if anyone here has had similar issues with unexplained fevers that cause chilblains? They typically form in the evenings and hurt like hell. It very mild case that is actually more sensitive to heat then cold. When i went off plaquenil i got fevers Stopping plaquenil. DailyStrength, Does Plaquenil help with Joint Pain? - Autoimmune diseases. Plaquenil and tylenol pmIs plaquenil safer than methotrexateHydroxychloroquine metabolismWhat is the cost of plaquenil When you have lupus, something happens to your body’s natural defense system your immune system to make it work incorrectly. Instead of only targeting bad things like viruses and bacteria, it also attacks healthy cells and tissues. There are several types of lupus, and every case is different. Lupus Symptoms Fatigue, Fever, Swollen Lymph Nodes, Rash, & More. Plaquenil and Bronchospasm / Cough. DailyStrength. Immune & Autoimmune - Lupus should I take Plaquenil now or wait?. Oct 22, 2019 In 2002 I got a new doctor that diagnosed me with SLE and started me on plaquenil. I don't remember exactly how long it took but after some months the fever went down. I have always had fatigue after my first flare and joints and muscle pain every day along with many respiratory infections and skin rashes. But the fever has stayed away. Aug 29, 2014 One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. May 05, 2010 I don't know if this is just the RA in full swing, or if it is a side effect of the Plaquenil. I have been running a low-grade fever around 99.8 for about. a week and a half now. It comes & goes and I can tell when it is up because I feel hot. My normal body temperature is low, around 97.5, so I don't know if 99.8 would be considered a fever.