It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil and elective surgery Plaquenil pulmonary fibrosis Malaria chloroquine proguanil Does plaquenil work on osteoarthritis Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Side effects bruising methotrexate plaquenil Does anyone take methotrexate and hydroxychloroquine., Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Plaquenil retinal screeningCan plaquenil reduce your spleen sizeSupplement chloroquine with antifungal medications as prescribedPlaquenil zon I was on both medis for 15 years for mixed connective disease. I recently stopped methotrexate due to lungs involvement, my pulmonologist decided to put me on cellcept.i had no majors side effects but a metal taste when I first started. Make sure you have a chest X-ray yearly and periodic labs work. Good luck. Methotrexate and plaquenil - @Kristinsaba1988.. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Long-Term Side Effects of Plaquenil for Rheumatoid.. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and. Prescribed for Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention, Rheumatoid Arthritis. Side Effects Prevention Tips. The good news These common side effects can often be short-circuited by taking a folic acid supplement. Folic acid is the synthetic form of folate. One study found that rheumatoid arthritis RA patients on methotrexate who took folic acid supplements lowered the risk of GI problems and mouth sores by 79 percent.