Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and nausea Quinine and chloroquine Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory. An allergic skin rash that is caused by medication may last for weeks before the source is identified and usually resolves once the medication is stopped. The Wrap Up If you suddenly become itchy and begin to break out in hives anywhere on your body, you may be experiencing an allergic rash. If they're coming and going more than likely it isn't the Plaquenil. From what I understand it is very rare for someone to have an allergic reaction to the Plaquenil and when they do that isn't how it shows up. Hopefull it's not the Plaquenil because this drug is really a very good drug for Lupus. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How long for plaquenil rash to go away Allergic reaction to plaquenil DailyStrength, How Long Does an Allergic Rash Last? Healthfully What plaquenil used forSpectral-domain optical coherence tomography in hydroxychloroquine retinopathyHydroxychloroquine medlineplus Aug 10, 2012 The plaquenil may or may not make the butterfly rash go away. There is no way to predict. Typically plaquenil takes 4 to 6 months to take full effect in controlling systemic lupus. It makes you a little less photosensitive as well. Please make sure you have a baseline field of vision test. It is just precautionary, but you do need a baseline. How long does it take for plaquenil to get rid of the lupus.. Plaqunil rash -. Allergic reaction to Plaquenil Lupus Forums at The Lupus Site. Mar 11, 2014 How long does it take to get better/go away? On prednisone, plaquenil hydroxychloroquine and colcrys. What are the dangers of long term use of prednisone for sle in low doses. Like 5mg. Got ezcema on hands from generic plaquenil hydroxychloroquine. What are other options? Plaquenil hydroxychloroquine 200mg is it causing itchy skin rash? Well, unfortunately, there is no “magic” answer to this question. Since there are so many varieties of allergic reactions on the skin, the time that takes for them to go away will vary. So, let us go through the most common allergic skin conditions and the time it takes for them to go away. Hydroxychloroquine may not prevent malaria in all cases. especially if you take it for a long time. Get medical help right away if you have any very. rash, itching/swelling especially of.