One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil help calcium Chloroquine resistant malaria vivax Chloroquine 750 mg Plaquenil walgreens Bull's-Eye Maculopathy. Hugo Mesquita Nogueira, M. D. and Rita Dinis Gama, M. D. A 64-year-old woman with systemic lupus erythematosus and normal renal function had received chloroquine at a dose. The American Academy of Ophthalmology recommendations for screening that were. The clinical picture of HCQ and CQ toxicity had been characterized classically as a bilateral bull’s-eye maculopathy, an appearance caused by a ring of parafoveal RPE depigmentation that spares a foveal island. Easterbrook M, et al. Recommendations on. Bull's eye maculopathy. Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil bull's eye maculopathy Multimodal Imaging in Plaquenil Toxicity, Recommendations on Screening for Chloroquine and. Plaquenil hydroxychloraquine doseageDoes plaquenil treat inflammationHydroxychloroquine prednisone adverse effects What does Plaquenil/hydroxychloroquine do to your eyes? The retina is the film in the back of your eyes. CQ and HCQ can both cause maculopathy or retinopathy. Prior to modern diagnostic techniques, your eye doctor was looking for bull’s eye maculopathy with a dilated exam. Plaquenil - Eye Doctor MD. Chloroquine retinopathy - Wikipedia. Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy. Bull’s eye maculopathy describes a number of different conditions in which there is a ring of pale-looking damage around a darker area of the macula. The macula can often appear to have circular bands of different shades of pink and orange. Age of onset and severity of sight loss varies, and it can be inherited in many ways. The presence of bull’s-eye maculopathy indicates the disease has been progressing for years, resulting in foveal thinning and likely vision loss. 8 SD-OCT is a highly sensitive and reproducible imaging modality used in the detection of Plaquenil retinal toxicity. The preferential loss of photoreceptor IS/OS junction makes SD-OCT an ideal tool. Hydroxychloroquine-Induced Retinal Toxicity; Ophthalmic Pearls. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. these findings do not explain the clinical pigmentary changes causing a bull’s-eye maculopathy.