PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of The recommended adult dosage is 200 to 400 mg (155 to 310 mg base) daily, administered as a single daily dose or in two divided doses. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Chloroquine nursing responsibilities Chloroquine dosing for lupus retina Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Hydroxychloroquine may inhibit P-glycoprotein P-gp. Digoxin is a substrate for P-gp transport. For patients on a stable digoxin regimen and initiating hydroxychloroquine, no initial dose adjustment of either drug has been advised; however, serum digoxin concentrations should be monitored and used for digoxin dose titration as clinically. Antimalarials improve lupus by decreasing autoantibody production. This protects against the damaging effects of ultraviolet light from the sun and other sources and improving skin lesions. The two types of antimalarials most often prescribed today for lupus are hydroxychloroquine Plaquenil® and chloroquine Aralen®. Unlike the rapid. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. 400 mg to 600 mg (310 to 465 mg base) daily, administered as a single daily dose or in two divided doses. Plaquenil dosage for lupus Plaquenil Oral Uses, Side Effects, Interactions., Plaquenil hydroxychloroquine sulfate dose, indications. Prophylaxis for international travel to chloroquine resistant areaChloroquine used whee Lupus Erythematosus. The recommended adult dosage is 200 to 400 mg 155 to 310 mg base daily, administered as a single daily dose or in two divided doses. Doses above 400 mg a day are not recommended. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Plaquenil Dosage Guide -. Medications used to treat lupus Lupus Foundation of America. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Usual Adult Dose for Systemic Lupus Erythematosus. Initial dose 400 mg 310 mg base orally 1 to 2 times a day; this dose may be continued for several weeks or months, depending on patient response Maintenance dose 200 to 400 mg 155 to 310 mg base orally daily Comments-Each dose should be taken with a meal or a glass of milk. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Plaquenil Hydroxychloroquine Plaquenil is a prescription medication approved by the Food and Drug Administration FDA to treat inflammation associated with lupus in people whose symptoms have not responded to drugs with lower risk for side effects. Plaquenil is also known by its drug name, Hydroxychloroquine.