Please review the following URL and make sure that it is spelled correctly. Joint damage worries and aching hands are no fun, and if you’re experiencing those kinds of problems because of rheumatoid arthritis you may have options that can help you feel better. Chloroquine from quinine Does plaquenil work like anxiety meds Well, about 2 weeks into my "stop" program, I suddenly realized it was helping me. It was so gradual that until I stopped, I didn't realize that I wasn't as tired all the time. I didn't ache quite so much, and my eyes and mouth weren't as dry. I started back up and it took me about a month to 2 months to get back on track. Hydroxychloroquine doesn’t work immediately. It may be 12 weeks or longer before you notice any benefit. Because it's a long-term treatment it's important to keep taking hydroxychloroquine unless you have severe side-effects Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Most people who take Plaquenil also take other medicines for pain and stiffness. The progression of RA may be diminished in severity and duration by the combination of medicines and therapy that work best as determined by you and your physician. There’s no cure for arthritis, which is unfortunate, but feeling better is definitely possible. How long til hydroxychloroquine to work How long does it take for predisone to start working for., Hydroxychloroquine Side-effects, uses, time to work Does plaquenil help with scarring alopeciaClinical pharmacokinetics and metabolism of chloroquineCan chloroquine abort pregnancyTeva-chloroquine dosagePlaquenil for rosacea Aug 16, 2010 Most people say about 6 months. It works over time. It's pretty suttle. One day all the sudden you will notice that your arms or legs or feet don't feel as bad as they used to. Not that it is a cure all but it usually does help. How long until Plaquenil started working?. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. RA and Hydroxychloroquine How Effective is it for Rheumatoid.. Oct 22, 2017 It can take up to 8 weeks or more before the medication really starts to have an effect and actually help an individual using the drug. Because hydroxychloroquine is so delayed in its onset, I usually give it 4-6 months before really deciding if it is working. On the second and third day, take each dose 12 hours apart. The 1st dose of the day on all three days should be at the same time. Coartem can be repeated every two, three, or four weeks. I suggest starting every 2 weeks and increase the time between each cycle as long as symptoms do not return on the off-medicine days. Anita- I had always heard that too - that even if you stopped it, it would take a long time before it was out of your system. I still believe this to be true, but I am convinced now that plaquenil must have multiple modes of action, one being long term effects, and one being something happening in the short term.