Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Best price hydroxychloroquine Plaquenil low stool siga Plaquenil 200 mg efectos secundarios Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, In particular, hydroxychloroquine Plaquenil® can cause retinal toxicity over time, particularly at high dosages. Annual comprehensive eye examinations are recommended by the American Optometric Association for people with lupus, especially for anyone taking Plaquenil. Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Eye problems caused by plaquenil The Risk of Retinal Toxicity with Plaquenil, How lupus affects the eyes Lupus Foundation of America Early plaquenil toxicity octHydroxychloroquine sulfate plaquenil side effectsChloroquine side effectsCost of generic plaquenilChloroquine drug The most common place for Hydroxychloroquine to cause a problem is in a ring of the macula surrounding the fovea which is demonstated in the visual field test you can see in the picture above. The black areas are the areas the patinet couldn't see well. What can Hydroxychloroquine Plaquenil do to my eyes?. New Plaquenil Guidelines. Plaquenil Side Effects on Your Eyes and Vision. Your eye care provider can examine the macula and detect subtle changes before you begin to notice any symptoms of problems. As a result, all patients taking plaquenil should have an examination approximately every six months. The macula should be examined through a dilated pupil. The incidence of Plaquenil related macular problems increases. Retinal problems that are caused by these drugs are usually seen when large doses are used, and are more common with chloroquine than the much more commonly used hydroxychloroquine Plaquenil®, but retinal toxicity can occasionally occur. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use.