While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "I started the hydroxychloroquine medication a week ago and within the first day or two noticed a big difference in my pain and fatigue with major improvement SLE. Chloroquine phoaphate powder Hydroxychloroquine sulfate davis I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness. Dec 11, 2010 The Plaquenil sadly didn't reduce or help my fatigue It did help with mouthsores and my rashes although. Fatigue can also be a side effect of medication. If fatigue hinders you, there are ways you can try to increase your energy with lupus. This article offers five key ways to cope with fatigue and. While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. Plaquenil (hydroxychloroquine) is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Can plaquenil help with fatigue Hydroxychloroquine User Reviews for Sjogren's. -, Did Plaquenil help your fatigue? - Sjogren's World Saposin b binds chloroquineMalaria chloroquine proguanilTreatment of uncomplicated malaria chloroquine Dec 05, 2017 Importantly, it tends to be very effective for a number of generalized symptoms such as joint pain and fatigue, and may help somewhat to control progression. As others have stated, it can take awhile to kick in, and as long as six months to reach full effect. Experiences taking Plaquenil for Fatigue and Muscle Pain.. Fighting Lupus Fatigue and Boosting Energy. Things that Changed My Life with Lupus Fatigue, Part 3. Plaquenil is a unique drug that helps control/suppress certain autoimmune symptoms. Plaquenil will not work for everyone with autoimmune issues. But there are other drugs like Erythromycin, Azithromycin, Doxycycline, Fluconazole, Malarone, ect. that may work better for your autoimmune condition. Sep 12, 2012 Plaquenil will also help with rashes. It does take awhile to build up in your system before you notice any results Make sure you see an eye doctor for a base line eye exam. If you use plaquenil there is a chance of a serious side effect, retinal damage.is important to get regular eye exams while you are taking this med. Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects.