Part of that is due to less exercise, part due to having no appetite thus feeling like anything I can get down is ok. Well, now I've been exercising at almost my pre-Lupus rate (ran a marathon a year before), eating a more moderate diet (clean protein, vegs & fruits), and am no longer taking that weight & bloat causing Prednisone (off Pred almost 2 yrs now). My question: Do you feel like you've gained weight on Plaquenil (ie without Prednisone)? Plaquenil and muscle relaxers interactions Scholarly articles plaquenil autoimmune encep halitis Hydroxychloroquine affects retina I have been on plaquenil for many a year, and it has not affected my weight at all. If you go to or rxlist.com, neither of them list weight gain as a side effect, while they both list "nausea, vomiting, stomach pain; loss of appetite, weight loss" as side effects. How good is Hydroxychloroquine, and any side effe. - LUPUS UK. LUPUS UK. 25,607 members • 21,035. Extensive muscle wasting which eventually resulted in a weight loss of about 40% and three near death experiences in approx. 6 years. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare. Does anyone know if hydroxychloroquine and methotrexate can cause weight loss. I took my 3rd dose of mtx this week as well as daily hydroxychloroquine and weekly folic acid. In 3 weeks I have lost just over half a stone. Week 1 I was very nauseous, week 2 improved and this week, I haven't thought about it. My Lupus has been really quiet for about 2 yrs, and I'm afraid to change anything. The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Hydroxychloroquine and weightloss Hydroxychloroquine Uses, Dosage & Side Effects -, How good is Hydroxychloroquine, and any side effe. Plaquenil works rheumatoid arthritisRisk of plaquenil retinopathyHow long does it take plaquenil retinopathy to reversePlaquenil side effects sunPlaquenil nightmares I saw the GI doctor today I am SO TIRED of seeing doctors and after our brief meeting, he has me scheduled for a colonoscopy and upper GI scope/biopsy!I am very underweight and do have chronic diarrhea, but gosh, this seems invasive as a first step in trying to figure out anyone had chronic diarrhea/weight loss from Plaquenil? Plaquenil, diarrhea and weight loss?. Does anyone know if hydroxychloroquine. - HealthUnlocked. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Here are 8 weight loss tips that you can ignore. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.