While the exact percentage of RA patients who experience sleep problems is hard to nail down, more than 80% of people with RA report fatigue as part of their symptoms. Why Sleep Matters Sleep problems can increase levels of stress hormones and aggravate flares, says Rochelle Rosian, MD, a Cleveland Clinic rheumatologist. When hydroxychloroquine treatment rheumatoid arthritis Does plaquenil weaken the immune system Cbd and plaquenil Plaquenil and Insomnia - from FDA reports Summary Insomnia is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Some medications, such as prednisone and hydroxychloroquine, also have the side effect of causing sleeplessness. It is a good idea to take these drugs earlier in the day to reduce this effect. “When you sleep, you make all those brain chemicals that you need to feel better. And even if you’re not flaring, you may not manage your pain as well if you’re not sleeping. Plaquenil and insomnia Hydroxychloroquine Oral Route Description and Brand Names., Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Stop taking plaquenil Jan 18, 2009 Plaquenil doesn't usually cause insomnia. It is most likely something else, such as prednisone if you're taking it or anxiety. Insomnia is a common complaint for people with Lupus, some as a result of the steroids and some from general stress of the disease. Started taking Plaquenil for Lupus and now I can't sleep. Any.. Rheumatoid arthritis and insomnia Tips for better sleep. Foods to Avoid When Taking Plaquenil Oral. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Plaquenil gave me anxiety and I could not sleep while taking a higher dose. You should probably call your doctor and tell them. Maybe they can adjust your milligrams to a lower dose to see if that is what is causing the insomnia. It is no fun not to be able to sleep, i hope you get this figured out and get some rest - Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.