Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil pregnancy category Plaquenil for sale Plaquenil birth control pills Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available. While used for restless legs syndrome, it is not recommended for this purpose due to the risk of side effects. It can be taken by mouth or used intravenously. The dosage of chloroquine phosphate is often expressed in terms of equivalent chloroquine base. Each 250 mg tablet of chloroquine phosphate is equivalent to 150 mg base. For malaria suppression Adult Dose 500 mg = 300 mg base on exactly the same day of each week. Chloroquine diphosphate salt powder or crystals, 98.5-101.0% dry basis Synonym N 4-7-Chloro-4-quinolinyl-N 1,N 1-dimethyl-1,4-pentanediamine diphosphate salt, N4-7-chloroquinolin-4-yl-N1,N1-diethylpentane-1,4-diamine diphosphate CAS Number 50-63-5. Empirical Formula Hill Notation C 18 H 26 ClN 3 2H 3 PO 4. Molecular Weight 515.86. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine base molecular weight Chloroquine C18H26ClN3 - PubChem, Chloroquine Phosphate Tablets - Chloroquine Phosphate Oral. Chloroquine raises ph Chloroquine. In some countries, this medicine may only be approved for veterinary use. In the US, Chloroquine chloroquine systemic is a member of the following drug classes amebicides, antimalarial quinolines and is used to treat Amebiasis, Malaria, Malaria Prevention and Sarcoidosis. Chloroquine -. Chloroquine diphosphate salt powder or crystals, 98.5-101.. Chloroquine - Wikipedia. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Each 500 mg tablet of Chloroquine phosphate contains the equivalent of 300 mg Chloroquine base. In infants and children the dosage is preferably calculated by body weight. Adult Dose The dosage for prophylaxis is 500 mg = 300 mg base administered once per week on exactly the same day of each week. Following oral administration of a single 600-mg dose of quinine sulfate in healthy adults, the mean plasma clearance was 0.08-0.47 L/hour per kg median 0.17 L/hour per kg and the mean plasma elimination half-life was 9.7-12.5 hours. Following oral administration of 10 mg/kg.