Clonidine transdermal

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  1. CROW07 New Member

    Clonidine transdermal


    Clonidine lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels to relax and your heart to beat more slowly and easily. Clonidine transdermal (skin patch) is used to treat hypertension (high blood pressure). It is sometimes used together with other blood pressure medications. Clonidine transdermal may also be used for purposes not listed in this medication guide. Do not use in larger or smaller amounts or for longer than recommended. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Apply the skin patch to a flat, hairless area of the chest, back, side, or outer side of your upper arm. Clonidine is a medicine for people who suffer from high blood pressure, but it also has applications in treating menopausal symptoms and in helping people stop smoking. It is available as a tablet and as a patch to put on the skin, which is the transdermal form of the drug. Clonidine transdermal patches typically stay on for a week before a new one needs to be applied. One of the ways clonidine works is to slow the beating of the heart. The drug also relaxes the muscular tension around blood vessels, which opens them up for the blood to move around under less pressure. Both of these actions help to reduce the amount of blood flowing around the body, and therefore lower the pressure of the blood. High blood pressure, which is also known as hypertension, is not a disease in itself.

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    Transdermal clonidine is used alone or in combination with other medications to treat high blood pressure. Clonidine is in a class of medications called centrally acting alpha-agonist hypotensive agents. Clonidine transdermal manufacturer/pricing. from transdermal patch 0.3 mg/24 h 1 box, 4 patches $334.91. Other Sections. Transdermal patch 0.1 mg patch q7Day initially; may increase by weekly 0.1-mg increments after 1-2 weeks if desired blood pressure reduction not achieved; not to exceed 0.6 mg/week ie, 2 clonidine 0.3 mg patches

    Find disease, condition, and injury fact sheets for more than 6500 conditions in our library. Browse several ways to find what interests you: use an A to Z Index (in English or Spanish), browse by condition name, or by categories of conditions such as those related to the respiratory system or to immunity disorders. This section of our Health Library is home to fact sheets about more than 1700 procedures. Find information about the procedure of interest to you in an A to Z listing (in English or Spanish) or by categories of procedures such as those related to bones and joints or brain and nerves. Learn about everything from Adenoidectomies to X-Rays. PO administration: 0.1-0.3 mg q4-6hr; increase by 0.1 mg/day to 0.15-0.75 mg/day if required; do not exceed 2.4 mg/day TD administration: 100-200 mcg/day patch q7Days; initiate 0.1-0.3 mg PO q4-6hr for first 2 days to allow for adequate drug levels Not recommended as routine treatment for hypertension (Beers criteria) Potential for orthostatic hypotension and adverse CNS effects May cause bradycardia Immediate release: Lower initial doses than for nongeriatric adult dosing, as well as gradual adjustments, are recommended Extended release: May require lower initial dose than for nongeriatric adult dosing Skin reactions; patch (15-50%) Dry mouth (40%) Somnolence (19-38%) Headache (19-29%) Fatigue (13-24%) Drowsiness (33%) Dizziness (13-16%) Hypotension, epidural (45%) Postural hypotension, epidural (32%) Anxiety (11%) Epidural clonidine is not recommended for obstetric postpartum or perioperative pain management because the risk of hemodynamic instability (eg, hypotension, bradycardia) may be unacceptable in this population Dilute product with strength of 500 mcg/m L prior to use Epidural: Hemodynamically unstable patients (risk of severe hypotension) Do not discontinue suddenly (risk of rebound hypertension) Patch: May need to remove if severe erythema and/or localized vesicle formation develop at application site or generalized rash; consult physician Severe coronary insufficiency May cause xerostomia Recent MI Cerebrovascular disease Chronic renal failure Raynaud's disease Thromboangiitis obliterans History of depression (may exacerbate depression in cancer patients) May impair ability to perform hazardous tasks Remove patch before MRI (may cause burns) Hypotension may occur; usually responsive to IV fluids and, if necessary, appropriate parenterally administered pressor agents Cardiac conduction abnormalities: Sympatholytic action may worsen sinus node dysfunction and atrioventricular (AV) block, especially if coadministered with other sympatholytic drugs Titrate slowly and monitor vital signs frequently in patients at risk for hypotension, heart block, bradycardia, syncope, cardiovascular disease, vascular disease, cerebrovascular disease or chronic renal failure; measure heart rate and blood pressure prior to initiation of therapy, following dose increases, and periodically while on therapy; avoid concomitant use of drugs with additive effects unless clinically indicated; advise patients to avoid becoming dehydrated or overheated Epidural administration may result in mild respiratory depression (usually with higher than recommended dose) Use with caution in cerebrovascular disease Avoid as first line antihypertensive in the elderly due to high risk for adverse side effects Children may be particularly susceptible to hypertensive episodes when experiencing GI illnesses that lead to vomiting Discontinue oral immediate release formulations within 4 hr of surgery; restart as soon as possible following surgery Due to different pharmacokinetic profiles, oral formulations are not interchangeable with extended release on a mg-mg basis due to different pharmacokinetic profiles Central sympatholytic via stimulation of central alpha receptors; results in reduced sympathetic outflow, causing decreased PVR, HR, BP, and renal vascular resistance; produces presynaptic and postjunctional alpha-2 adrenoreceptor analgesia by preventing pain signal transmission to brain Postsynaptic alpha2-agonist stimulation may regulate subcortical activity in the prefrontal cortex, which may regulate the area of the brain responsible for attention, emotions, and behaviors, and thereby reduces hyperactivity, distractibility, and impulsiveness The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

    Clonidine transdermal

    Clonidine Patches Indications, Side Effects, Warnings -, Clonidine transdermal Manufacturer/Pricing - Epocrates Online

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  3. A transdermal patch is a patch that attaches to your skin and contains medication. The drug from the patch is absorbed into your body over a period of time.

    • Transdermal Patches How to Apply Them - Healthline.
    • Catapres, Catapres-TTS clonidine dosing, indications..
    • Clonidine transdermal Uses, Side Effects & Warnings -.

    May 5, 2017. System structure and components. CLONIDINE TRANSDERMAL SYSTEM USP is a multi-layered film, 0.25 mm thick, containing clonidine as. Transdermal clonidine is effective as monotherapy in mild-moderate hypertension, and in combination with diuretics, calcium antagonists and ACE inhibitors in. Clonidine transdermal skin patch is used to treat hypertension high blood pressure. It is sometimes used together with other blood pressure medications. Clonidine transdermal may also be used for purposes not listed in this medication guide.

     
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