Additionally, another exception occurred while executing the custom error page for the first exception. Plaquenil (Hydroxychloroquine sulfate) is a drug originally used to prevent or treat malaria. Side effects of chloroquine malaria pills Plaquenil vision side effects Aug 18, 2011 Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong. The antimalarial drug hydroxychloroquine HCQ is able to have immune modulatory effects including the reduction of inflammatory cytokine production and of immunoglobulin IgG levels, and a down-modulation of natural killer cell activity; these properties have warranted its use in some of the autoimmune conditions. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Now the drug is used to treat inflammatory diseases. Malaria is a serious but rare disease caused by bites from infected mosquitos. Hydroxychloroquine iris Hydroxychloroquine Side Effects, Dosage, Uses, and More, Case report Use of hydroxychloroquine in Immune. Plaquenil side effects skin rashCan i take ed pills with hydroxychloroquine used forSkin cancer side effect of plaquenilAralen 150 mg para que sirveWhat to do if taking plaquenil makes you nauseous The most important risk factors included the daily dose of hydroxychloroquine and duration of use. People who took 4 to 5 mg/kg/day of hydroxychloroquine had a much lower cumulative risk as compared to people you took a higher dose 1% risk in the first 5 years and less than 2% up to 10 years. Will hydroxychloroquine hurt my eyes? - RheumDoctor. Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening. Iritis Causes, Symptoms, Tests and Treatment. Hydroxychloroquine treatment for 24 weeks reduced systemic interferon-stimulated gene expression in SS. Hydroxychloroquine treatment for 24 weeks improved ESR, IgG and IgM levels in SS. Hydroxychloroquine treatment for 24 weeks did not improve disease activity scores in SS. The Link between Eye Problems and Lupus Medications. Many eye problems in patients with lupus originate from the drugs doctors use to treat lupus itself. Three groups of medications prescribed for lupus patients are immunosuppressive drugs such as methotrexate and mycophenolate, antimalarials such as hydroxychloroquine Plaquenil®, and. Hydroxychloroquine HCQ has been used for therapy of rheumatologic disorders since the 1950s. Ocular toxicity associated with HCQ use was initially described in the 1960s 1, 2. The incidence of HCQ retinopathy is estimated at 1 % after consumption of HCQ for 5 years. It is marked by paracentral and central scotoma and decreased color vision.