Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Arthritis medication hydroxychloroquine What are the side effects of plaquenil Where is sandoz plaquenil produced Eyes hydroxychloroquine The dosage of chloroquine phosphate is often expressed or calculated as the base. Each 250 mg tablet of chloroquine phosphate is equivalent to 150 mg base. In infants and children the dosage is preferably calculated on the body weight. Malaria Suppression— Adult Dose 500 mg = 300 mg base on exactly the same day of each week. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before. chloroquine is only effective against malaria from certain areas of the world. chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine phosphate molecular weight Chloroquine - FDA prescribing information, side effects and uses, Chloroquine C18H26ClN3 - PubChem Chikungunya disease and chloroquine treatmentPlaquenil eye screeningChloroquine phosphate injection dosage Kg or more 1 g chloroquine phosphate 600 mg base orally as an initial dose, followed by 500 mg chloroquine phosphate 300 mg base orally after 6 to 8 hours, then 500 mg chloroquine phosphate 300 mg base orally once a day on the next 2 consecutive days Chloroquine Dosage Guide with Precautions -. Compare Plaquenil vs Chloroquine -. Chloroquine Hydrochloride Drug Information, Professional. Molecular Weight 418 g/mol Computed by PubChem 2.1 PubChem release 20 Hydrogen Bond Donor Count 3 Computed by Cactvs 22.214.171.124 PubChem release 20 Hydrogen Bond Acceptor Count 7 Computed by Cactvs 126.96.36.199 PubChem release 20 Rotatable Bond Count 8 Computed by Cactvs 188.8.131.52 PubChem release 20 Exact Mass 417.148905 g/mol Description 1.1 Name, Formula, Molecular Weight The chemical name of chloroquine phosphate i n Chemical Abstracts is found under t h e heading Quinoline and designated as 7-Chloro- 4- 4-diethylamino-1-methylbutylamino Iquinoline diphosphate. Molecular Weight 515.86. Beilstein/REAXYS Number 4223142. EC Number 200-055-2. Chloroquine is a member of quinolone family and is a weak intercalating agent.