The condition is related to homeostatic systems utilised by the body to control the blood sugar level. It is described as a sense of tiredness, lethargy, irritation, or hangover, although the effects can be lessened if a lot of physical activity is undertaken in the first few hours after food consumption. The alleged mechanism for the feeling of a crash is correlated with an abnormally rapid rise in blood glucose after eating. This normally leads to insulin secretion (known as an insulin spike), which in turn initiates rapid glucose uptake by tissues, either storing it as glycogen or utilizing it for energy production. The consequent fall in blood glucose is indicated as the reason for the "sugar crash". Another cause might be hysteresis effect of insulin action, i.e., the effect of insulin is still prominent even if both plasma glucose and insulin levels were already low, causing a plasma glucose level eventually much lower than the baseline level. Sugar crashes are not to be confused with the after-effects of consuming large amounts of protein, which produces fatigue akin to a sugar crash, but are instead the result of the body prioritising the digestion of ingested food. Medications known as glucocorticoids, such as prednisone and cortisone, are mainly used as anti-inflammatories or as anti-rejection drugs. They are prescribed, for example, for an arthritis attack or after an organ transplant. One of their side effects is to increase blood glucose (sugar) since these drugs promote glucose production in the liver and reduce the sensitivity of the cells to insulin. Consequently, glucose accumulates in the blood and can cause a rise in blood sugar levels. The side-effects vary from person to person based on the prescribed dose of glucocorticoids, the way it is administered (cream, tablets or injection), and the length of time a person takes the drug. If you are taking glucocorticoids, measure your blood sugar more often than usual in order to monitor the drug’s impact on your diabetes control. It may be necessary to talk to your doctor to adjust your antidiabetes medication or your insulin dosage to maintain normal blood-glucose levels.
However, persistent, unexplained hypoglycemia can indicate a potentially. Prednisone Deltasone was prescribed for joint inflammation in a. Jun 16, 2008. Carry treatment for hypoglycemia glucose tablets, juice, candy with. It's hard for me to know if coming off the prednisone and the steroid.