Articles on Difference are general information, and are not intended to substitute for professional advice. You agree that we have no liability for any damages. Glipizide is an oral medication that is used to treat Type 2 diabetes. The drug is available in immediate-release tablets and extended-release tablets. Patients who currently take the medication as part of their diabetes treatment state that Glipizide has helped with lowering their blood sugar levels, and it seems that the extended-release tablets are favored over the immediate-release tablets. One of the main benefits from the drug is that it helps to lower your A1C levels by 1-2%. We will discuss the benefits and the downsides of Glipizide in more detail below. Glipizide is an oral medication used in the treatment of Type 2 diabetes. It is available in brand-name form as well as generic form, with the brand-names being Glucotrol and Glucotrol XL.
An easy way to check this is to go to the sepalika home page, and right up there is the “Drug Side Effect” Tool. You just have to enter your drug name – either brand name or, like in your case, just enter “Glipizide and Metformin” and click Get Solutions. This throws up the results page that shows the vitamins and nutrients depleted by long term use of metformin and glipizide. You can use this tool to test for different drugs, both for yourself or for friends and family. Long term use of metformin and glipizide can deplete Vitamin B12, Folic Acid and Coenzyme Q10. This can lead to a variety of side effects, from fatigue to tingling hands and legs, to memory and cognition issues, skin issues, mouth ulcers, muscle pains and cardiac issues (including irregular heart beat). Several dietary supplements have been proven to help with blood sugar control. Doses provided as glipizide-metformin -Initial Therapy in Patients with Inadequate Glycemic Control on Diet and Exercise Alone: Starting dose: 2.5 mg-250 mg orally once a day -Consider a starting dose of 2.5 mg-500 mg orally twice a day for patients with fasting blood glucose (FBG) between 280 and 320 mg/d L Maintenance Dose: Increase in increments of 2.5 mg-500 mg per day every 2 weeks to the minimum effective dose to achieve adequate blood glucose control Maximum Initial Dose: 10 mg-1000 mg or 10 mg-2000 mg per day in divided doses -Patients with Inadequate Glycemic Control on a Glipizide (or another Sulfonylurea) and /or Metformin: Initial dose: 2.5 mg-500 mg or 5 mg-500 mg orally twice a day Maintenance Dose: Increase in increments of no more than 5 mg-500 mg to the minimum effective dose to achieve adequate blood glucose control Maximum Dose: 20 mg-2000 mg per day Comments: -Give with meals; initial doses should be conservative to avoid hypoglycemia largely due to glipizide and gastrointestinal side effects largely due to metformin. -For patients who are switching to combination therapy, initial doses should not exceed the daily dose of glipizide (or equivalent sulfonylurea) and metformin already being taken; the decision to switch to the nearest equivalent dose should be based on clinical judgement. -Monitor patients closely for signs and symptoms of hypoglycemia. Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. -Contraindicated in patients with renal disease (e.g. males with serum creatinine levels of 1.5 mg/d L or greater, females with serum creatinine of 1.4 or greater, or abnormal creatinine clearance). New Metformin Renal Dosing: Obtain e GFR prior to initiating therapy: -e GFR less than 30 m L/min/1.73 m2: Use is contraindicated -e GFR 30 to 45 m L/min/1.73 m2: Initiating therapy is not recommended -e GFR that falls below 30 m L/min/1.73 m2 during therapy: Discontinue therapy -e GFR that falls below 45 m L/min/1.73 m2 during therapy: Assess risks versus benefit of continued therapy -e GFR greater than 45 m L/min/1.73 m2: No dose adjustments recommended -Contraindicated in patients with conditions that may cause renal disease or renal dysfunction such as cardiovascular collapse (shock), acute myocardial infarction and septicemia.
This is not a list of all drugs or health problems that interact with glipizide and metformin. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take glipizide and metformin with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Initial treatment: start at 2.5 mg/250 mg (glipizide/metformin) PO q Day with food If fasting plasma glucose = 280-320 mg/d L: 2.5/500 mg PO q12hr Titrate q2week to no more than 10/2000 mg per day in divided doses Discontinue metformin at the time of or before an iodinated contrast imaging procedure in patients with an e GFR between 30-60 m L/minute/1.73 m²; in patients with a history of liver disease, alcoholism, or heart failure; or in patients who will be administered intra-arterial iodinate contrast The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.
Find patient medical information for Glipizide-Metformin Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user. Long term use of metformin and glipizide can deplete Vitamin B12, Folic Acid and Coenzyme Q10. This can lead to a variety of side effects, from fatigue to.