Patients and methods: In a double-blind, randomized phase III study, breast cancer patients suffering from hot flashes at least twice a day, who were not taking any medication against hypertension and depression received either clonidine 0.075 mg twice a day or venlafaxine 37.5 mg twice a day for 4 weeks. Tel: -7024; Fax: -7938; E-mail: [email protected]: Classical hormone replacement therapy for hot flashes is contraindicated in breast cancer especially in endocrine responsive disease. Goethe-University Hospital, Department of Obstetrics and Gynecology, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. The primary end point was defined as the frequency of hot flashes after 4 weeks of treatment. A self-reported 1-week hot flash and other symptom questionnaire were kept before the start of treatment until the end of treatment course. Results: From April 2002 to October 2004, 80 patients were recruited of whom 64 were assessable for efficacy analyses. Thirty-three received clonidine and 31 venlafaxine, nine patients stopped early because of side-effects and seven withdrew consent. Also known as: Catapres, Kapvay The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care."This instantly stopped my hot flushes , also helped my moods . I still have the odd flush or night sweats but not bad at all . I get the occasional hot flush if I eat too many fatty foods. I'm finding also its got my blood pressure under control and helped with pain associated with a spinal disease. It does take a LONG time to be effective, though, about 6 weeks. Highly recommend but please make sure doctor prescribes your dose , as this drug does lower blood pressure .""I had hot flushes, night sweats AND day sweats after having to stop taking HRT because of breast cysts. I went back to my Dr to increase the dose to 1 1/2 tablets a day, which eliminated my symptoms. Don't stop taking them, just because you don't think that are going to work!!!!! I don't like taking medications if I don't have to, but I was desperate to find relief. I can now sleep at night.""I had used Bioidentical HRT for about 10 years until I had an abnormal mammogram with calcifications. Even though I tapered down, I soon began having night sweats and hot flashes again. I have been using only 0.1 MG once a day instead of twice a day as directed, mainly because I simply can't remember to take it twice. So far, I think it's doing what it's intended.
Jan 17, 2007. Clonidine, a centrally active α-adrenergic agonist, that reduces vascular reactivity, and which is widely used as a nonestrogenic treatment of hot. Reviews and ratings for clonidine when used in the treatment of. "I started this medication because my hot flashes and night sweats were out of control.