J Am Acad Child Adolesc Psychiatry 1996;35(10):1304-13. Those that occur are usually minor, transient, and disappear as patients develop tolerance within days of starting medication. Medication treatment strategies in the MTA study: relevance to clinicians and researchers. Sleep disturbances in children with attention deficit/hyperactivity disorder. For most patients, the optimal psychostimulant dosage produces few or no side effects. The following strategies can minimize these effects. Evidence-based pharmacotherapy for attention-deficit hyperactivity disorder. Appetite suppression and insomnia—both common, dose-related side effects of psychostimulants—can jeopardize treatment adherence for patients with attention-deficit/hyperactivity disorder (ADHD). He is director of the Attention Disorders Treatment Center, Denver, CO. Dodson is a board-certified psychiatrist specializing in adult ADHD. The two most commonly used stimulants—methylphenidate and amphetamine—cause similar side effects. Clonidine belongs to a class of drugs called central alpha-adrenergic agonists. In the United States, clonidine tablets are sold under the brand name Catapres and clonidine skin patches are sold under the brand name Catapres-TTS. There is also an injectable form that is administered directly into the spinal cord for the treatment of postoperative pain. Clonidine tablets and patches are approved by the United States Food and Drug Administration (FDA) for the treatment of high blood pressure. However, clonidine has been found to be useful in the treatment of alcohol, opiate, and nicotine withdrawal syndromes, attention-deficit/hyperactivity disorder (ADHD), and Tourette's syndrome, one of the tic disorders . Clonidine was synthesized in 1960s and was initially tested as a nasal decongestant. In the United States, clonidine was first used to treat hypertension although it has also been investigated for treatment of different neuropsychiatric disorders. Clonidine works on specific nerve cells in the brain that are responsible for lowering blood pressure, slowing heart rate, and decreasing the body's reaction to the withdrawal of chemicals like alcohol, opiates, cocaine, and nicotine.
Psychiatry Clin Neurosci. 2004 Apr;582138-44. Clonidine effects on all-night human sleep opposite action of low- and medium-dose clonidine on human. Sep 17, 2017. Like many other medications on the market today, clonidine can have some pretty beneficial applications. Hypertension, ADHD, insomnia, and.